Research Associate II - Stem Cell Discovery Research
The individual in this position works independently and as part of a team whose goal is to develop stem cell based therapeutics to treat age-related degenerative disease. Emphasis is on evaluating candidates for stem cell based therapeutics using biochemical and functional assays. Candidate must have extensive experience in mammalian cell culture including scale-up, maintenance and storage of cells. Prefer candidates skilled in pluripotent stem cell culture and differentiation including induced pluripotent stem cells and embryonic stem cells. Must be experienced in development and evaluation of biochemical, immunological and cell-based assays. Experience with basic molecular biology techniques is also highly desirable. The research associate should contribute to innovation of new products including developing innovative ways to identify and develop new therapeutic candidate cell lines or cell product candidates such as exosomes.
Responsibilities
Growth, maintenance and screening of candidate clonal cell lines for various structural and functional properties.
Preparation and characterization of extracellular vesicles from conditioned medium
Screening candidates for regenerative properties using cell-based assays for such as migration, proliferation, and angiogenesis
Screening therapeutic candidates using immunological, biochemical and functional assays.
Performing gene expression analysis of RNA and Protein.
Performs small and large scale culture of stem cell lines for production of master and working cell banks
Expertise in data management and analysis systems
Troubleshoots complex problems in creative and effective ways; actively participates with innovation and/or optimization of established processes to ensure product development and work plan timelines are met. Compiles processes and analyzes data; records research procedures and results; files and maintains records; inputs and retrieves data from databases. Functions effectively as a part of both functional and cross-functional teamsMS/MA in Molecular Biology, Cellular Biology, or related field, industry experience preferred.
BS/BA in Molecular Biology, Cellular Biology, Immunology or related field with at least 3 years' experience, industry experience preferred.
Knowledge and Skills
Strong experience in in-vitro cell-base functional assays
Strong experience with mammalian tissue culture practices including iPS and hES is required
Extracellular vesicle experience preferred
Experience in immunology, immunostaining, and flow cytometry desirable
Experience with routine molecular biology methods is desirable
Well organized data collection and data management
Excellent written and verbal communication skills are required.Estimated Salary: $20 to $28 per hour based on qualifications.
Responsibilities
Growth, maintenance and screening of candidate clonal cell lines for various structural and functional properties.
Preparation and characterization of extracellular vesicles from conditioned medium
Screening candidates for regenerative properties using cell-based assays for such as migration, proliferation, and angiogenesis
Screening therapeutic candidates using immunological, biochemical and functional assays.
Performing gene expression analysis of RNA and Protein.
Performs small and large scale culture of stem cell lines for production of master and working cell banks
Expertise in data management and analysis systems
Troubleshoots complex problems in creative and effective ways; actively participates with innovation and/or optimization of established processes to ensure product development and work plan timelines are met. Compiles processes and analyzes data; records research procedures and results; files and maintains records; inputs and retrieves data from databases. Functions effectively as a part of both functional and cross-functional teamsMS/MA in Molecular Biology, Cellular Biology, or related field, industry experience preferred.
BS/BA in Molecular Biology, Cellular Biology, Immunology or related field with at least 3 years' experience, industry experience preferred.
Knowledge and Skills
Strong experience in in-vitro cell-base functional assays
Strong experience with mammalian tissue culture practices including iPS and hES is required
Extracellular vesicle experience preferred
Experience in immunology, immunostaining, and flow cytometry desirable
Experience with routine molecular biology methods is desirable
Well organized data collection and data management
Excellent written and verbal communication skills are required.Estimated Salary: $20 to $28 per hour based on qualifications.
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